[Bioc-devel] New seqPattern package
Vanja Haberle
vanja.haberle at gmail.com
Mon Jan 12 16:29:21 CET 2015
Dear Bioconductor members,
I'd like to draw your attention to the new package for visualisation of
oligonucleotide patterns and motif occurrences across a set of sorted
sequences.
The *seqPattern* package is now available in the development branch:
http://www.bioconductor.org/packages/devel/bioc/html/seqPattern.html
This package is designed to visualise sequence patterns across a large
set of sequences
(/e.g/. promoters, enhancers, ChIPseq peaks, /etc./) centred at a common
reference position (/e.g./ TSS, peak position) and ordered by some
feature. The visualisations include plotting the density of occurrences
of di-, tri-, and in general any oligo-nucleotides, consensus
sequences specified using IUPAC nucleotide ambiguity codes and motifs
specified by a position weight matrix (PWM). Such visualisations are
useful in discovering sequence patterns
positionally constrained with respect to the reference point and their
correlation with the
specified feature.
Your comments and suggestions are welcome and will assist in
continuously improving the package.
Kind regards,
Vanja
--
Vanja Haberle, PhD
Postdoctoral Training Scientist
Computational Regulatory Genomics Group
MRC Clinical Sciences Centre
Hammersmith Hospital Campus
Du Cane Road
London W12 0NN, UK
vanja.haberle at csc.mrc.ac.uk
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