Dear all, What are your thoughts about adding a new generic to BiocGenerics: setGeneric("compare", function(x, y, ...) setGeneric("compare")) I have spotted a couple of existing cases on CRAN (lava (S3) and NMF (S4) with signature function(object, ...)) and CMA::compare (with a very different signature) on Bioc (maintainer cc'ed). Best wishes, Laurent