paulsen {boot}R Documentation

Neurotransmission in Guinea Pig Brains


The paulsen data frame has 346 rows and 1 columns.

Sections were prepared from the brain of adult guinea pigs. Spontaneous currents that flowed into individual brain cells were then recorded and the peak amplitude of each current measured. The aim of the experiment was to see if the current flow was quantal in nature (i.e. that it is not a single burst but instead is built up of many smaller bursts of current). If the current was indeed quantal then it would be expected that the distribution of the current amplitude would be multimodal with modes at regular intervals. The modes would be expected to decrease in magnitude for higher current amplitudes.




This data frame contains the following column:


The current flowing into individual brain cells. The currents are measured in pico-amperes.


The data were kindly made available by Dr. O. Paulsen from the Department of Pharmacology at the University of Oxford.

Paulsen, O. and Heggelund, P. (1994) The quantal size at retinogeniculate synapses determined from spontaneous and evoked EPSCs in guinea-pig thalamic slices. Journal of Physiology, 480, 505–511.


Davison, A.C. and Hinkley, D.V. (1997) Bootstrap Methods and Their Application. Cambridge University Press.

[Package boot version 1.3-30 Index]