richCluster: Fast, Robust Clustering Algorithms for Gene Enrichment Data

Clusters functionally related biological terms from gene set enrichment results. Terms are compared by the overlap of their gene sets using Cohen's kappa, the Jaccard index, or the Dice coefficient, and the resulting similarity matrix is grouped either by agglomerative hierarchical clustering with single, complete, average, or Ward linkage, or by the seed-and-merge procedure of the 'DAVID' functional classification tool. The distance and clustering routines are written in 'C++' for speed. The methods are described in Huang et al. (2007) <doi:10.1186/gb-2007-8-9-r183>, Ward (1963) <doi:10.1080/01621459.1963.10500845>, Cohen (1960) <doi:10.1177/001316446002000104>, and Jaccard (1912) <doi:10.1111/j.1469-8137.1912.tb05611.x>.

Version: 2.0.0
Depends: R (≥ 3.5.0)
Imports: dplyr, fields, heatmaply, igraph, magrittr, networkD3, plotly, Rcpp (≥ 1.0.14), stats, tidyr, viridis
LinkingTo: Rcpp
Suggests: devtools, knitr, rmarkdown, roxygen2, testthat
Published: 2026-09-16
DOI: 10.32614/CRAN.package.richCluster
Author: Junguk Hur ORCID iD [aut, cre], Sarah Hong [aut], Jane Kim [aut]
Maintainer: Junguk Hur <hurlabshared at gmail.com>
BugReports: https://github.com/hurlab/richCluster/issues
License: GPL-3
URL: https://github.com/hurlab/richCluster
NeedsCompilation: yes
Materials: NEWS
CRAN checks: richCluster results

Documentation:

Reference manual: richCluster.html , richCluster.pdf
Vignettes: Workflow: richCluster Example (source, R code)

Downloads:

Package source: richCluster_2.0.0.tar.gz
Windows binaries: r-devel: richCluster_2.0.0.zip, r-release: richCluster_1.0.2.zip, r-oldrel: richCluster_1.0.2.zip
macOS binaries: r-release (arm64): richCluster_1.0.2.tgz, r-oldrel (arm64): richCluster_2.0.0.tgz, r-release (x86_64): richCluster_2.0.0.tgz, r-oldrel (x86_64): richCluster_2.0.0.tgz
Old sources: richCluster archive

Linking:

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