nlmixr2lib

Version 0.2.0

• Work with the new rxode2 version 2.0.12 model() and ini() assignment methods.
• Therapeutic-area specific models have begun being added.
• Models can now give the user some additional information load via the message meta-data.
• Models can now be in different directories. The change is for ease of maintaining the library, it is not a change that affects users.
• A regression where addEta() did not change the parameter, related to a change in rxode2, was fixed.
• addEta() detects where to add etas more robustly when covariates are on the parameter.

Models added

• Add Davda (2014) mAb consensus model
• Add Liu (2017) time-dependent clearance model based on nivolumab
• Add Kovalenko (2020) dupilumab PK model
• Add Soehoel (2022) tralokinumab PK model
• Add Zhu (2017) lebrikizumab PK model

Version 0.1.0

• Initial version