mrMLM.GUI: Multi-Locus Random-SNP-Effect Mixed Linear Model Tools for Genome-Wide Association Study with Graphical User Interface

Conduct multi-locus genome-wide association study under the framework of multi-locus random-SNP-effect mixed linear model (mrMLM). First, each marker on the genome is scanned. Bonferroni correction is replaced by a less stringent selection criterion for significant test. Then, all the markers that are potentially associated with the trait are included in a multi-locus genetic model, their effects are estimated by empirical Bayes and all the nonzero effects were further identified by likelihood ratio test for true QTL. Wen YJ, Zhang H, Ni YL, Huang B, Zhang J, Feng JY, Wang SB, Dunwell JM, Zhang YM, Wu R (2018) <doi:10.1093/bib/bbw145>.

Version: 4.0.2
Depends: R (≥ 3.5.0), shiny, lars
Imports: Rcpp (≥ 0.12.14), methods, foreach, ncvreg, coin, shinyjs, data.table, doParallel, sampling, bigmemory, mrMLM, sbl
LinkingTo: Rcpp, RcppEigen
Published: 2020-10-08
DOI: 10.32614/CRAN.package.mrMLM.GUI
Author: Zhang Ya-Wen, Li Pei, and Zhang Yuan-Ming
Maintainer: Yuanming Zhang <soyzhang at>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: mrMLM.GUI results


Reference manual: mrMLM.GUI.pdf


Package source: mrMLM.GUI_4.0.2.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): mrMLM.GUI_4.0.2.tgz, r-oldrel (arm64): mrMLM.GUI_4.0.2.tgz, r-release (x86_64): mrMLM.GUI_4.0.2.tgz, r-oldrel (x86_64): mrMLM.GUI_4.0.2.tgz
Old sources: mrMLM.GUI archive


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