Package: WSSmod
Title: Weighted Sum Scores for Protein Network Modules
Version: 0.1.0
Authors@R: c(
    person("Robert", "Butler", , "rrbutler@stanford.edu", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0003-0200-8682")),
    person("WSSmod authors", role = "cph")
  )
Description: Computes Weighted Sum Score (WSS) module-level summaries from
    proteomic data. Protein-level values are sign-aligned to their association
    with core biomarkers and combined within 'STRING' network modules, weighted
    by network connectivity and association strength. Bundled reference modules
    and a fitted 'joinet' model also allow all module scores to be predicted
    from age, sex and a small panel of plasma biomarkers, without measuring the
    full proteomic panel. The method is described in Butler et al. (2026)
    <doi:10.64898/2026.08.14.26360394>.
License: MIT + file LICENSE
Encoding: UTF-8
Language: en-US
RoxygenNote: 7.3.2
Depends: R (>= 3.5.0)
Imports: data.table
Suggests: glmnet, joinet, knitr, rmarkdown, RNOmni, testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
LazyData: true
URL: https://github.com/Longo-Lab/WSSmod,
        https://Longo-Lab.github.io/WSSmod/
BugReports: https://github.com/Longo-Lab/WSSmod/issues
NeedsCompilation: no
Packaged: 2026-10-22 02:57:36 UTC; rrbutler
Author: Robert Butler [aut, cre] (ORCID:
    <https://orcid.org/0000-0003-0200-8682>),
  WSSmod authors [cph]
Maintainer: Robert Butler <rrbutler@stanford.edu>
Repository: CRAN
Date/Publication: 2026-11-03 16:00:38 UTC
