SfS - Research Seminar

Networks of proteins called signalling networks play a key role in the control of diverse cellular processes; their aberrant functioning is heavily implicated in many diseases, including cancer. Aberrations in cancer cells are thought to perturb the normal connectivity of these networks, with important biological and therapeutic implications. Yet cancer-specific signalling remains poorly understood, especially at the level of relevant (post-translational) protein modifications. However, modern high-throughput biochemical technologies are now able to make measurements on components of these systems, and can, in principle, shed light on a variety of open questions concerning signalling in cancer. I will discuss statistical approaches for interpreting these data, in particular how graphical models can be used to integrate biochemical data and prior knowledge of signalling biology to facilitate the discovery process.

Speakers:

Sach Mukherjee

Mar. 5, 2010

Michael McAleer

tba

15:15-17:00

Speakers:

Michael McAleer (Erasmus University, Rotterdam)

Mar. 19, 2010

Francis Bach

tba

15:15-17:00

Speakers:

Francis Bach (Paris)

Mar. 26, 2010

Cun-Hui Zhang

tba

15:15-17:00

URL:

http://stat.ethz.ch/talks/research_seminar

Speakers:

Cun-Hui Zhang

Further information: sekretariat@stat.math.ethz.ch

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