Statistics for Biomolecular Data Integration and Modeling - Workshop, Ascona 2007
- Scope:
- Development of high throughput assay technologies has rapidly transformed the field of molecular biology. Sequencing of the human genome and improvements in measurement technologies for DNA, RNA and proteins have revolutionized biological research, resulting in vast amounts of diverse types of quantitative data. Some examples of biological data types are sequence data at both the DNA and protein level, proteomics data collected by a variety of different technologies, protein-protein interaction data, gene copy number at loci throughout the genome, genotyping data via SNP arrays and gene expression data as quantified by microarrays.
In order to use the abundance of information to significantly advance biological understanding, fundamentally sound quantitative methods for combination of the manifold data types are required. Appropriate data integration gives researchers power to uncover meaningful biological relationships, enabling further understanding, targeted followup and efficient use of resources.
General areas where statistics has already and can continue to make significant contributions include: analysis methods for single data types, meta-analysis of microarray data, Bayesian and kernel methods for data combination, modeling of genetic networks and development of new methods in statistical computing.
- Date:
- June 10th -- 15th, 2007
- Slides of talks and posters
- Photos and short videos
Location: Centro Stefano Franscini Ascona, Switzerland
- Keynote Speakers:
- Jane Fridlyand (UC San Francisco), Robert Gentleman (Fred Hutchinson Cancer Research Center Seattle), Jelle Goeman (Leiden University), Haiyan Huang (UC Berkeley), Wolfgang Huber (EMBL-EBI Cambridge, UK), Trey Ideker (UC San Diego), Rafael Irizarry (Johns Hopkins Baltimore), Shirley Liu (Harvard, Cambridge MA), Lars Steinmetz (EMBL Heidelberg), Simon Tavare (University of Southern California, USA and Cambridge, UK), Liste of Participants
- Organizing Commitee:
- Peter Buhlmann, Anthony Davison, Darlene Goldstein
This workshop is sponsored by the Swiss National Science Foundation, Centro Stefano Franscini, Novartis Basel, Roche Basel, Serono Geneva, Syngenta Basel